Email this article Comparison of recurrent rate of gingival pigmentation after treatment by liquid nitrogen and cryoprob in 18 months follows-up
Abstract
Background: Cryosurgery is one of the simplest, most effective gingival depigmentation methods.
Repigmentation may happen after a while in each method. The aim of this study is to compare the
recurrence rate after treatment by liquid nitrogen swap and a cryoprob in 18 months.
Materials and Methods: A total of 26 patients with physiologic gingival pigmentation were selected.
The anterior sextant was divided into left and right segments; each segment was treated randomly
by swap technique or cryoprob. Standard photos were evaluated with photoshop software (Red,
Green, Blue, Cyan, Magenta, Yellow, Black [RGB, CMYK]) before and at 2 week, 1, 3, 6, 9, 12, 15,
18 months after the treatment. The results were compared, by the independent t-test and repeated
measure ANOVA thereafter least signifi cant difference post-hoc. The viewpoints of patients and
physicians regarding the treatment outcomes were obtained by a questionnaire and consequently
evaluated qualitatively by McNemar test (P < 0.05 was considered as signifi cant level).
Results: The statistical analysis showed a signifi cant difference in color change after the treatment
during 18 months, in each group (P < 0.001). The mean values of RGB had signifi cantly increased
after 2 weeks in both methods (P < 0.001), but the differences from 2 weeks to 18 months after
treatment were not signifi cant (P > 0.05). The mean values of CMYK signifi cantly decreased after
2 weeks in both methods (P < 0.001), but the differences from 2 weeks to 18 months after treatment
were not signifi cant (P > 0.05). Qualitative evaluation showed the preference of the cryosurgery
with swap method (P < 0.001). No signifi cant recurrence was observed during 18 months follow-up.
Conclusion: Both methods of cryosurgery are appropriate in treatment of gingival depigmentation
because no signifi cant recurrence was observed during 18 months follow-up.
Key Words: Cryosurgery, gingiva, nitrogen, nitrous oxide, pigmentation
Repigmentation may happen after a while in each method. The aim of this study is to compare the
recurrence rate after treatment by liquid nitrogen swap and a cryoprob in 18 months.
Materials and Methods: A total of 26 patients with physiologic gingival pigmentation were selected.
The anterior sextant was divided into left and right segments; each segment was treated randomly
by swap technique or cryoprob. Standard photos were evaluated with photoshop software (Red,
Green, Blue, Cyan, Magenta, Yellow, Black [RGB, CMYK]) before and at 2 week, 1, 3, 6, 9, 12, 15,
18 months after the treatment. The results were compared, by the independent t-test and repeated
measure ANOVA thereafter least signifi cant difference post-hoc. The viewpoints of patients and
physicians regarding the treatment outcomes were obtained by a questionnaire and consequently
evaluated qualitatively by McNemar test (P < 0.05 was considered as signifi cant level).
Results: The statistical analysis showed a signifi cant difference in color change after the treatment
during 18 months, in each group (P < 0.001). The mean values of RGB had signifi cantly increased
after 2 weeks in both methods (P < 0.001), but the differences from 2 weeks to 18 months after
treatment were not signifi cant (P > 0.05). The mean values of CMYK signifi cantly decreased after
2 weeks in both methods (P < 0.001), but the differences from 2 weeks to 18 months after treatment
were not signifi cant (P > 0.05). Qualitative evaluation showed the preference of the cryosurgery
with swap method (P < 0.001). No signifi cant recurrence was observed during 18 months follow-up.
Conclusion: Both methods of cryosurgery are appropriate in treatment of gingival depigmentation
because no signifi cant recurrence was observed during 18 months follow-up.
Key Words: Cryosurgery, gingiva, nitrogen, nitrous oxide, pigmentation
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