Oral manifestations in liver transplant recipients

Abstract

The article “oral manifestation in transplant patients” was

read with enthusiasm.[1] However, the following points

may be noted worthy. Fissured tongue, atrophy of tongue

papillae, and angular cheilitis can be observed in liver

transplant patients and these may be due to concurrent

hyposalivation, due to intake of diuretic drugs such

as thiazides and loop diuretics.[2,3] Excessive bleeding

with serious complications are encountered in the liver

transplant patients when they undergo simple procedures

such as scaling, tooth extraction, minor periodontal surgery,

and administration of local anesthetics.[4] These patients

exhibit hemostatic abnormalities such as prolonged

prothrombin time, activated partial thromboplastin

time; increased international normalized ratio and low

platelet count. Primary wound closure, Vitamin K 10 mg

intramuscularly, and use of topical thrombin and fi brin

glue along with antifi brinolytic agents such as oxidized

cellulose tranexamic acid and amino-caproic acid may be

helpful to control oral bleeding due to dental procedures 

The article “oral manifestation in transplant patients” was

read with enthusiasm.[1] However, the following points

may be noted worthy. Fissured tongue, atrophy of tongue

papillae, and angular cheilitis can be observed in liver

transplant patients and these may be due to concurrent

hyposalivation, due to intake of diuretic drugs such

as thiazides and loop diuretics.[2,3] Excessive bleeding

with serious complications are encountered in the liver

transplant patients when they undergo simple procedures

such as scaling, tooth extraction, minor periodontal surgery,

and administration of local anesthetics.[4] These patients

exhibit hemostatic abnormalities such as prolonged

prothrombin time, activated partial thromboplastin

time; increased international normalized ratio and low

platelet count. Primary wound closure, Vitamin K 10 mg

intramuscularly, and use of topical thrombin and fi brin

glue along with antifi brinolytic agents such as oxidized

cellulose tranexamic acid and amino-caproic acid may be

helpful to control oral bleeding due to dental procedures