Isfahan University of Medical SciencesDental Research Journal1735-33272120080120Evaluation of Relation Between Recurrent Aphthous Stomatitis and Stress2424P.Ghalayani. drj@dnt.mui.ac.irM.Karimi bijaninejad20101106Background and aim "Recurrent Aphthous Stomatitis" is an ulcer that appears in the Oral mucosa in the form of painful and often recurrent ulcers. Its prevalence is 10 to 20 percents. And in some of the selected groups such as students, its prevalence is up to 50 percents. Its appearance in female is more than male. No single reason has been recognized for this disease. Some of sources have referred to the relation of this disease with stress. The purpose of this study was to survey the role of stress as one of the factors that create recurrent aphthous stomatitis Methods and Materials This is a case-control study, in this study 61 patients with aphthous stomatitis that had been referred to the oral medicine department and affiliated clinics were examined. 61 patients were selected from two sexes randomly. Control group was consisted of the siblings of the patients who had been referred and selected randomly. After patient justification, Diagnosis and attestation of the professor, the “Standard questionnaire for measuring stress” in the name of “Klementz & Raberts” was completed by the patients and control group.The information was analyzed statistically through T-Test. Discussion The obtained information indicated that the average of stress mark in case and control group was 384 and 249 respectively. T-Test indicated that there was a significant difference between stress mark in two case an control groups (P