Effect of hydrogen peroxide and its combination with nano-hydroxyapatite or nano‑bioactive glass on the enamel demineralization and tooth color: An in vitro study

Abstract

Background: Patient demand for esthetic dental treatments is increasing, and among different
techniques, tooth bleaching is a popular procedure for smile improvement. There is a controversy
over the demineralizing effect of hydrogen peroxide (HP) containing bleaching agents on
tooth enamel. The aim of this study was to evaluate the effect of HP and its combinations with
hydroxyapatite (HA) and bioactive glass (BG) on enamel demineralization and tooth color changes.
Materials and Methods: Three groups of 20 teeth were used. Bleaching regimens included
HP alone, HP + HA, and HP + BG. Bleaching was repeated at six periods of 15 min. Energy
dispersive spectrometry was performed to evaluate calcium, phosphorus, sodium, magnesium, and
fluoride content of superficial enamel before and after bleaching. Tooth color was evaluated by
spectrophotometer before and after bleaching and ΔE values were calculated. Data were statistically
analyzed using SPSS version 17.
Results: Ca and P content was increased significantly in group HP + BG (P < 0.05). There was no
significant difference in ΔE values between the three groups (P > 0.05).(p value = 0.34).
Conclusion: Addition of BG to HP can increase superficial enamel mineral content after bleaching
and has no effect on tooth color changes in comparison to HP alone.
Key Words: Bioglass, hydrogen peroxide, hydroxyapatites, tooth bleaching

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Elham Kheradmand: Pubmed,Google Scholar