Comparative evaluation of remineralizing efficacy of calcium sodium phosphosilicate, ginger, turmeric, and fluoride

Abstract

Background: White lesions, also known as white spots, are the earliest signs of tooth decay. At
this stage, noninvasive preventive treatments, such as fluoride application, can help to slow down
or even reverse the progression of white lesions. For decades, fluoride has held the spotlight as
the go‑to agent in oral preventive care, demonstrating significant remineralizing power. Recent
scientific literature reveals a growing interest in alternative products as natural substances that
demonstrate potential remineralizing effects on tooth enamel. This in vitro study aimed to evaluate
the potential remineralizing effect of calcium sodium phosphosilicate (CSP), ginger, and turmeric.
Materials and Methods: This in vitro study was designed to evaluate the remineralizing effects
of various materials on the enamel of extracted human teeth. The aim was to compare the
effectiveness of these different substances in promoting enamel remineralization. Enamel blocks were
prepared and were divided into seven experimental groups: CSP, fluoride toothpaste, nonfluoride
toothpaste, turmeric, ginger, fluoride varnish, and distilled water. In this study, sample mineralization
is assessed through the quantitative photo‑induced fluorescence test before demineralization, after
demineralization, and after remineralization. Statistical analysis of the data was conducted using a
one‑factor analysis of variance test. The significance level was set at P < 0.05.
Results: The best results were obtained by groups treated with turmeric (P < 0.0001), Enamelast
fluoride varnish (P < 0.0001), and NovaMin (P < 0.01), as compared to other remineralizing
treatments.
Conclusion: While fluoride has undeniably revolutionized oral preventive care, the exploration of
alternative products as natural substances and innovative compounds in recent scientific literature
signals a shift in focus toward safer and potentially more diverse options.
Key Words: Curcuma, fluorides, tooth remineralization, Zingiber officinale

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 Amir Shayegan: Pubmed,Google Scholar