Isfahan University of Medical SciencesDental Research Journal1735-33279120120218Effect of MTAD on the shear bond strength of self-etch adhesives to dentin891891ENVajihesadatMortazaviDental Research Center and Department of Restorative Dentistry, School of Dentistry, Isfahan University of Medical Sciences,Isfahan, Iran. v_mortazavi@dnt.mui.ac.irAbbasaliKhademiKazemKhosraviMohammadhosseinFathiMohammadesmaeilEbrahimi –ChaharomShirinShahnaseriNavidKhalighinejadHamidBadrian20120218Background: As the use of different irrigants to eliminate residual debris and smear layer inthe field of endodontic is unavoidable, by considering the effect of irrigants on the bond strengthof resin composite restorations, this study was designed to evaluate the effect of a mixture of atetracycline isomer, an acid, and a detergent (MTAD) on the shear bond strength of two self-etchadhesives, Clearfil SE Bond and Adper Prompt L- Pop to dentin.Materials and Methods: The crowns of 80 extracted premolars were transversally sectioned toexpose dentin. Flat dentin surfaces were wet abraded with 320-grit abrasive paper and randomlyassigned to eight groups according to two self-etch adhesive and four dentin surface treatments:direct application over smear layer (no treatment), etching with 35% phosphoric acid for 15s, 1min 5.25% NaOCl/1 min MTAD and 20min 1.3% NaOCl/5min MTAD. Shear bond strength wastested 24 h after storage in distilled water at 37ºC in incubator. Data were analyzed using one-wayANOVA followed by duncan post-hoc (α=0.05).Results: Phosphoric acid etching prior to SE Bond application significantly decreased the shear bondstrength to dentin (P<0.05). Application of MTAD clinical protocol (20min 1.3% NaOCl/5min MTAD)did not significantly decrease the shear bond strength of self-etch adhesives to dentin (P=0.745)Conclusions: Based on the results of present investigation, it seems that the use of clinical protocolof 1.3% NaOCl as a root canal irrigant and a 5-min application of MTAD as a final rinse to removethe smear layer has no adverse effect on the shear bond strength of self-etch adhesives to dentin.Key Words: Adhesives, bond strength, smear layer, MTAD