Effect of photobiomodulation on postoperative endodontic pain: A systematic review of clinical trials

Abstract

Background: This review aims to perform a complete evaluation of the impact of
photobiomodulation (PMB) on postoperative endodontic pain.
Materials and Methods: The PRISMA checklist was used to perform this systematic review. The
electronic databases were searched, including Google Scholar, PubMed, and Embase. Sixty‑three
papers were obtained through a main electronic search and a hand search. Nine trials met the
criteria after screening the titles, abstracts, and/or full texts.
Results: Seven out of nine studies showed that PMB has a significant impact on relieving
postoperative endodontic pain, with no statistically significant difference in the severity of pain
between the laser and control groups in the two remaining studies. In addition, eight studies
showed no adverse effects, indicating that we can remove the adverse effects of drugs such as
nonsteroidal anti‑inflammatory drugs. However, one study showed evidence of the consequences
of PMB application on teeth with symptomatic irreversible pulpitis. Therefore, it can be concluded
that PMB should not be used in teeth with pain because of irreversible pulpitis.
Conclusion: Although there is some understanding from a cellular viewpoint of the effects of
PMB, there is still some uncertainty about whether these cell‑level modifications impact reducing
the postendodontic pain.
Key Words: Clinical trial, low‑level light therapy, pain, review, root canal therapy

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Seyyed Amir Seyyedi : Pubmed,Google Scholar