DERJ DERJ Dent Res J Dent Res J Dental Research Journal 1735-3327 2008-0255 Wolters Kluwer - Medknow India DERJ-22-20 00003 10.4103/drj.drj_479_23 2 Systematic Review Customized versus titanium healing abutments for preimplant tissue healing in fresh socket implants: A systematic review Mosharraf Ramin 1 Fathi Amirhossein 1 Rismanchian Mansour 2 Ghasemi Ehsan 2 Givehchian Pirooz 2 piroozgivehchian@gmail.com Department of Prosthodontics, Dental Materials Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Department of Prosthodontics, Dental Implants Research Center, Dental Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Address for correspondence: Dr. Pirooz Givehchian, Department of Prosthodontics, Dental Implants Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran. E-mail: piroozgivehchian@gmail.com 05 2025 22 05 2025 22 1 10.4103/drj.drj_479_23 21 07 2023 26 11 2024 06 01 2025 © 2025 Dental Research Journal 2025 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License (http://creativecommons.org/licenses/by-nc-sa/4.0/), which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. ABSTRACT Background:

It is suggested to use a customized abutment confirming to the configuration of the new extraction socket. Since there are no systematic reviews regarding this issue, the aim of this systematic review was to assess the efficacy of customized healing abutments versus titanium healing abutments on peri-implant tissue healing in fresh socket implants to improve the treatment prognosis in the clinic.

Materials and Methods:

Electronic searches were conducted on PubMed/MEDLINE, Embase, Cochrane, and Google Scholar databases by the end of June 2022. All randomized controlled studies, prospective, retrospective, human studies of preimplant tissue healing around customized or titanium healing abutments, follow-up studies of more than 6 months, and in English were included in this study. The exclusion criteria were studies that were not clinical, with a follow-up period of <6 months, and those that assessed abutment healing.

Results:

Forty-six studies were obtained following database research. Based on the eligibility criteria, five studies were finally included. Qualitative data analysis showed that two studies reported that customized abutments caused a significant decrease in a buccolingual width while two others did not report accurate results. Furthermore, one study only pointed to the significance of this change within 1 month after implant placement. Consequently, customized healing abutments may cause higher volume changes in the presence of thin bone phenotypes and facilitate the closure of large sockets. In addition, these investigations reported the same implant survival rate during the follow-up period for both methods.

Conclusion:

Customized healing abutments exhibit efficacy in sealing immediate implant sockets, particularly in cases with thin bone phenotypes. These abutments induce significant volume changes, aiding in the closure of larger sockets and thereby preserving the socket volume.

Key Words: Customized healing abutment fresh socket titanium healing abutments OPEN-ACCESS TRUE
INTRODUCTION

Immediate implantation of the implant in the extraction site reduces surgical cases, the length of the treatment period, and the patient’s feeling of satisfaction with the healing process. However, using an implant immediately after extraction may cause thinning of the jawbone. This can also cause a facial recession and esthetic problems.[1-3]

The thickness of the bone plate and gingiva play an essential role in the outcome of a successful surgery on an immediate implant. Furthermore, a suitable distance between the implant and the bone is critical in reconstructing and forming new bone around implants.[4,5]

Filling the gap between the implant and the socket wall with bone filler compounds can benefit the aesthetic results of the immediate implant. For example, the filling materials in the gap of the extraction cavity can protect the gingiva and bone structure. Still, it may damage the temporary crown or cause problems in significant gaps.[6,7] Based on the results of clinical studies, it is suggested to use a customized abutment similar to the structure of the new extraction socket.

The study by Choorak et al. evaluated the soft-tissue change after placing an immediate implant with a customized healing abutment on posterior teeth in a 6-month follow-up.[8] Fernandes et al. demonstrated that the immediate use of implants, along with bone substitutes and collagen matrices, could reduce the amount of erosion in the areas surrounding the implant. Therefore, customized healing abutments can be proposed as an alternative for sealing the socket and maintaining the soft tissue contour. Fernandes et al. studied the changes in peri-implant tissues after using custom-healing abutments compared to xenogeneic collagen matrices in flapless maxillary immediate implant implantation.[9] Hu et al. investigated the changes in the hard and soft tissue around immediate implants using two types of abutments.[10] Menchini-Fabris et al. examined the two different methods of tissue recovery on the alveolar ridge width over 3 years after implant placement in a fresh extraction socket.[11] Giovanni-Battista et al. compared customized and standard therapeutic abutments, evaluating alveolar bone in new socket implants.[12] However, the results of previous studies are not in agreement with each other. In addition, there are no systematic reviews regarding this issue. The aim of this study is to systematically review the efficacy of customized healing abutments versus titanium healing abutments for peri-implant tissue healing in fresh socket implants.

MATERIALS AND METHODS Study design

This study was designed based on the Cochrane[13] criteria for systematic review and reported cases as per the Preferred Reporting Elements for Systematic Reviews and Meta-analyses.[14]

Search strategy

Literature searches in the following databases, including the PubMed, MEDLINE, Embase, Google Scholar, and Cochrane databases, were conducted using the appropriate keyword (MeSH). The clinical issue (PICO) was organized according to the population (patients receiving implants), intervention (patients with customized abutment), comparison (comparison with patients with standard abutment), and outcome (preimplant tissue healing as the main outcome). The searched words were: customized healing abutment OR titanium healing abutments AND preimplant tissue healing AND fresh socket implants.

Inclusion and exclusion criteria

Inclusion criteria included the following: All randomized controlled studies, prospective, retrospective, human studies of preimplant tissue healing around customized or titanium healing abutments, follow-up superior to 6 months, and in English. The exclusion criteria were studies that were not clinical, the with follow-up period was <6 months, and studies that assessed abutment healing. Table 1 shows the inclusion and exclusion criteria of the selected articles.

Inclusion exclusion criteria of selected studies

Search strategy and data extraction

Literature searches in the following databases, including the PubMed MEDLINE, Embase, Cochrane databases, and first 100 hit of Google Scholar, were conducted using the appropriate keyword June 2022. The searched words were: customized healing abutment OR titanium healing abutments AND preimplant tissue healing AND fresh socket implants [Table 2]. In addition, the reference list of selected papers was searched. The search results were exported to EndNote, where duplicate publications were identified and eliminated. The studies were screened based on the title and abstract. Then, the articles were selected by full-text screening following the eligibility criteria. Studies without the required information were excluded. The data included were extracted using a predesigned data sheet. The electronic database search, study selection and data extraction were done by two independent researchers. In case of disagreement, a third researcher was consulted to solve the problem.

Specific search strategy for each database

RESULTS

Searching the databases resulted in the retrieval of 46 recorded [Figure 1]. Only 25 titles and abstracts of the paper were selected based on comparative inclusion and exclusion criteria. After reading all the articles, the other 20 studies were omitted because they lacked the required information. A diagram of the research workflow is shown in Figure 1. A total of 5 studies were included in the study for qualitative evaluation, including one randomized controlled trial study,[9] two prospective clinical studies[8,10] and two retrospective experiences.[11,12] The total number of implants in these five studies involved 170 oral implants in 123 patients. Table 1 presents the main results of the surveys. In the study of Choorak et al., patients received immediate implants through bone grafting and customized healing abutment. Before, immediately, and 1, 3, and 6 months after extraction, silicone molds were prepared, scanned, and measured. The obtained data were analyzed by Friedman and Wilcoxon tests.[8] A study by Fernandes et al. was designed as a prospective, randomized, controlled clinical trial. In this study, patients were divided into two groups depending on the socket sealing option: In one group, collagen matrix was used, and in the other group, the customized abutment was used. They took digital casts before extraction and 1, 4, and 12 months after implant placement to determine linear and volumetric changes between different time points in the peri-implant tissue areas.[9] Hu et al. used a modified osteotomy technique to place 28 immediate implants in molar/premolar sockets in their study. They also used protein-free bovine bone minerals to bridge the implants’ gaps. The implants of the control group were connected using titanium healing abutments, and the treatment group was connected using customized healing abutments and were followed up for 6 months.[10] In the study of Menchini-Fabris et al., the sockets were immediately implanted after tooth extraction. The implants were reviewed retrospectively in two groups. First, the conventional group was treated with a standard package with a cover screw. In contrast, in the custom group, a custom abutment made with computer-aided design (CAD)/computer-aided manufacturing (CAM) technology was immediately screwed onto the head, and the width of the alveolar ridge was measured at 3 years.[11] Giovanni-Battista et al. immediately implanted the postextractive sockets without filling the space between the implant surface and the socket wall. In addition, they measured the width of the alveolar ridge after implant placement with or without a custom abutment up to 3 years after surgery [Table 3].[12]

Flow chart for studies were identified, displayed and included in the study.

DISCUSSION

In general, for planning a suitable treatment plan for each individual, the decision to use a customized abutment is complicated. However, clinical information is needed to help practitioners decide. Therefore, the results of this systematic review may help make an appropriate treatment decision. The present study investigated the effect of two groups of implants associated with different therapeutic abutments on the initial healing process [Table 3].

Baseline characteristics of studies assessing the customized healing abutment

Studies have shown that implant components play a role in inducing a local or systemic inflammatory reaction.[15] Using acrylic materials in combination with customized abutments can cause allergies in sensitive people and disrupt the healing process. Therefore, there is a need to use tissue-compatible compounds in the manufacture of customized abutments. The declaration of the study by Choorak et al. was that immediate implant placement with customized healing abutment could maintain the architecture and horizontal dimension of transmucosal tissue but can keep the vertical measurement of lingual height and buccolingual width during 6 months’ follow-up.[8]

That study also showed that the soft-tissue made the most significant changes in the 1st month, and after that, the tissue dimensions remained constant except for the buccal side. During 3 months, the buccolingual width changed significantly. Furthermore, after 6 months of follow-up, lingual height showed a significant difference.[8]

The findings of Fernandes et al. showed a significant difference between the average values of buccal volume in the 1st month in both groups during 1 year of follow-up. Still, this difference was not practical for 1 year between the two groups. Furthermore, no significant difference was observed in the change of midfacial mucosa and papilla between the groups.[9]

Hu et al. showed that the amount of buccal and lingual bone loss was comparable between the two groups. Changes in buccal bone thickness were similar between the two groups, and the soft-tissue surface of the middle face was well preserved in both groups.[10]

The findings of the study by Menchini-Fabris et al. showed that the survival rate of 54 dental implants for all implants was reported as 100% after 36 months. However, the decrease in bone width for the customized group was significantly smaller than that of the conventional group.[11]

Giovanni-Battista et al. reported that the survival rate of all 54 implants after 36 months was 100%. The bone width decreased in both groups, and the change in dimensions of the alveolar ridge in the customized group was insignificant compared to the standard group. Furthermosre, they observed a significant difference between the groups regarding tooth type. In comparison to the other teeth (2.57 ± 0.53 mm and 2.36 ± 0.32 in the canine and premolar sites, respectively), the incisor teeth appeared to have considerably less bone loss (with a bone loss of 1.59 ± 0.44 mm).[12]

The study’s conclusion by Fernandes et al. was that both treatment options could be predictable solutions for sealing immediate implant sockets. However, higher volume changes can be expected in the presence of thin bone phenotypes.[9] Hu et al. concluded that despite study limitations, for immediate implants placed in posterior sockets, customized healing abutments can facilitate the closure of large sockets. Despite more pronounced incomplete filling, healing abutments composed of ketone polyether ether and resin did not pose an increased risk of peri-implant bone loss or soft-tissue resorption during the initial healing period.[10]

Correcting and solving the problems of healing abutments can improve their performance. When there is a need to make customized therapeutic abutments with polished surfaces in the shortest possible time, using computer tools to prepare an ideal abutment can be very helpful.[16-18] The results of the study by Menchini-Fabris et al. showed that the CAD/CAM method could have advantages such as stabilization of bone volume in a new socket implant, and it also causes constant growth of teeth for restorative veneers. Finally, optimal prosthetic-surgical planning and minimally invasive extraction are necessary to maintain the integrity of the supporting tissue.[11]

An abutment with convenient features can help improve gingivally and bone tissue when immediate implant placement. Therefore, it can be effective in maintaining the socket’s volume and the final restoration. During extraction, it is necessary to use customized abutments to protect the beauty and anatomy of the gingival, and it is considered the last step in implant surgery.[19-21] Giovanni-Battista et al. stated that the customized method could help protect and support the natural appearance profile by creating a seal over the surgical site and preserving the socket volume.[12]

Consequently, these findings illuminate the critical significance of material selection for therapeutic abutments, emphasizing the need for tissue-compatible compounds to avert allergic reactions and disruptions in the healing process, especially with immediate implant placement. Customized healing abutments, while maintaining tissue architecture and facilitating socket closure, necessitate attention to specific materials, such as ketone polyether ether and resin, to prevent adverse effects on bone loss or tissue resorption during initial healing stages. Incorporating CAD/CAM technology emerges as a promising avenue for expedited production of ideal abutments and stabilizing bone volume in new implant sockets.

This systematic review’s limitations were confined to using only indexed publications in online databases and English articles. Hence, the authors recommend evaluating articles and studies from additional sources such as gray literature, books, and articles in different languages.

CONCLUSION

The study concludes that both treatment options could be predictable solutions for sealing immediate implant sockets. However, customized healing abutments exhibit efficacy in sealing immediate implant sockets, particularly in cases with thin bone phenotypes. These abutments induce significant volume changes such as size, aiding in the closure of larger sockets and thereby preserving the socket volume.

Financial support and sponsorship

Nil.

Conflicts of interest

The authors of this manuscript declare that they have no conflicts of interest, real or perceived, financial or non-financial in this article.

REFERENCES Evans CD , Chen ST . Esthetic outcomes of immediate implant placements. Clin Oral Implants Res 2008;19:7380. Stavropoulos A , Sima C , Sima A , Nyengaard J , Karring T , Sculean A . Histological evaluation of healing after transalveolar maxillary sinus augmentation with bioglass and autogenous bone. Clin Oral Implants Res 2012;23:12531. Benic GI , Mokti M , Chen CJ , Weber HP , Hämmerle CH , Gallucci GO . Dimensions of buccal bone and mucosa at immediately placed implants after 7 years:A clinical and cone beam computed tomography study. Clin Oral Implants Res 2012;23:5606. Morton D , Chen ST , Martin WC , Levine RA , Buser D . Consensus statements and recommended clinical procedures regarding optimizing esthetic outcomes in implant dentistry. Int J Oral Maxillofac Implants 2014;29:21620. Buser D , Chappuis V , Belser UC , Chen S . Implant placement post extraction in esthetic single tooth sites:When immediate, when early, when late?. Periodontol 2000 2017;73:84102. Trimpou G , Weigl P , Krebs M , Parvini P , Nentwig GH . Rationale for esthetic tissue preservation of a fresh extraction socket by an implant treatment concept simulating a tooth replantation. Dent Traumatol 2010;26:10511. Castelnuovo J , Sönmez AB . The autogenous immediate implant supported single-tooth restoration:A 5-year follow-up. Eur J Esthet Dent 2012;7:38295. Choorak N , Amornsettachai P , Chuenjitkuntaworn B , Suphangul S . Dimensional change of peri-implant soft tissue following immediate implant placement and customized healing abutment in posterior teeth. J Int Dent Med Res 2021;14:2739. Fernandes D , Nunes S , López-Castro G , Marques T , Montero J , Borges T . Effect of customized healing abutments on the peri-implant linear and volumetric tissue changes at maxillary immediate implant sites:A 1-year prospective randomized clinical trial. Clin Implant Dent Relat Res 2021;23:74557. Hu C , Lin W , Gong T , Zuo Y , Qu Y , Man Y . Early healing of immediate implants connected with two types of healing abutments:A prospective cohort study. Implant Dent 2018;27:64652. Menchini-Fabris GB , Crespi R , Toti P , Crespi G , Rubino L , Covani U . A 3-year retrospective study of fresh socket implants:CAD/CAM customized healing abutment versus cover screws. Int J Comput Dent 2020;23:10917. Giovanni-Battista MF , Ugo C , Paolo T , Giovanni C , Luigi R , Roberto C . Customized versus conventional abutments in healing fresh extraction dental sockets on maxillary anterior teeth. Int J Prosthodont Restor Dent 2019;9:827. Green S , Higgins JP . Cochrane Handbook for Systematic Reviews of Interventions. The Cochrane Collaboration and John Wiley &Sons Ltd 2011 Page MJ , McKenzie JE , Bossuyt PM , Boutron I , Hoffmann TC , Mulrow CD . The PRISMA 2020 statement:An updated guideline for reporting systematic reviews. BMJ 2021;372:n71 Al-Wattar WM , Al-Wattar WM , Al-Radha AS . Microbiological and cytological response to dental implant healing abutment. J Int Dent Med Res 2017;10:8918. Proussaefs P . Custom CAD-CAM healing abutment and impression coping milled from a poly (methyl methacrylate) block and bonded to a titanium insert. J Prosthet Dent 2016;116:65762. Finelle G , Lee SJ . Guided immediate implant placement with wound closure by computer-aided design/computer-assisted manufacture sealing socket abutment:Case report. Int J Oral Maxillofac Implants 2017;32:e637. Lee JH , Sohn DS . Accelerated peri-implant soft tissue conditioning with computer-aided design and computer-aided manufacturing technology and surgical intervention:A case report. Implant Dent 2015;24:7425. Tarnow DP , Chu SJ . Human histologic verification of osseointegration of an immediate implant placed into a fresh extraction socket with excessive gap distance without primary flap closure, graft, or membrane:A case report. Int J Periodontics Restorative Dent 2011;31:51521. Franchi M , Fini M , Martini D , Orsini E , Leonardi L , Ruggeri A . Biological fixation of endosseous implants. Micron 2005;36:66571. Akin R . A new concept in maintaining the emergence profile in immediate posterior implant placement:The anatomic harmony abutment. J Oral Maxillofac Surg 2016;74:238592.

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