Evaluation of the effect of a nanobioglass varnish and Er,Cr:YSGG laser on remineralization of demineralized deciduous teeth

Abstract

Background: This in vitro experimental study aimed to evaluate and compare the remineralizing
effects of nanobioglass varnish and Er, Cr: YSGG laser on demineralized deciduous teeth as potential
alternatives to fluoride therapy.
Materials and Methods: This in vitro experimental study was conducted to evaluate and compare
the remineralizing effects of nanobioglass varnish and Er,Cr: YSGG laser on demineralized deciduous
teeth. Eighty‑four extracted primary incisors were randomly assigned to seven groups, including
positive and negative controls, fluoride varnish, nanobioglass varnish, Er,Cr:YSGG laser, and combined
varnish–laser treatments. Bioactive glass nanoparticles were synthesized by the sol‑gel method and
characterized using X‑ray diffraction, Fourier transform infrared spectroscopy, and transmission
electron microscopy. Surface microhardness was measured using the Vickers hardness test. Data
were analyzed using the one‑way analysis of variance and independent t‑tests using the SPSS software
version 23 at a significance level of 0.05.
Results: Significant differences in surface microhardness were observed among the
groups (P < 0.0001). The nanobioglass varnish followed by laser irradiation group showed the
highest improvement in enamel microhardness compared to other treatments.
Conclusion: Er,Cr:YSGG laser, either alone or in combination with nanobioglass varnish, significantly
enhances the remineralization of demineralized deciduous enamel. This combination may serve as
an effective nonfluoride alternative for managing primary caries lesions.
Key Words: Bioactive glasses, dental caries, fluorides, hardness tests, tooth demineralization, tooth remineralization, topical

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Zahra Khosravi: Pubmed,Google Scholar