An experimental study on the effect of four pediatric drug types on color stability in different tooth‑colored restorative materials

Abstract

Background: One of the drawbacks of tooth‑colored dental restorations is their discoloration over
time. The present study aimed to determine the effect of four categories of pediatric medications,
including analgesics, antibiotics, anticonvulsants, and multivitamins, on two types of tooth‑colored
dental materials, namely, composite resins and glass ionomer cements.
Materials and Methods: In this in vitro study, a total of 40 specimens with disc shapes
(with a diameter of 5 mm and thickness of 2 mm) were prepared from each material and immersed
in eight different drugs for 2 min three times a day for 1 week. The values of the baseline color
were calculated based on the CIE (International Commission on Illumination) L*a*b* system. After
7 days, ΔE values were calculated. Two‑way analysis of variance was employed for statistical analysis.
Statistical significance was defined at 0.05.
Results: Statistical analysis showed that there were significant differences between ΔE and different
restorative materials as well as ΔE and drug types (P < 0.001).
Conclusion: According to the results of this in vitro study, all the four types of drugs caused the
discoloration in all the restorative materials, and the color change values were affected by the type
of used drug and restorative material.
Key Words: Antibiotic dental restorations, discoloration, spectrophotometry